External factors accelerate expression divergence between duplicate genes
نویسندگان
چکیده
منابع مشابه
External factors accelerate expression divergence between duplicate genes.
We examined the evolution of expression of duplicate genes in Arabidopsis thaliana, by analyzing 512 data sets of gene expression microarrays and 2022 recent duplicate gene pairs. Expression divergence between gene duplicates is significantly greater in response to environmental stress than to developmental processes. A slow rate of expression divergence during development might offer dosage-de...
متن کاملExpression divergence between duplicate genes.
A general picture of the role of expression divergence in the evolution of duplicate genes is emerging, thanks to the availability of completely sequenced genomes and functional genomic data, such as microarray data. It is now clear that expression divergence, regulatory-motif divergence and coding-sequence divergence all increase with the age of duplicate genes, although their exact interrelat...
متن کاملDivergence in the spatial pattern of gene expression between human duplicate genes.
Microarray gene expression data provide a wealth of information for elucidating the mode and tempo of molecular evolution. In the present study,we analyze the spatial expression pattern of human duplicate gene pairs by using oligonucleotide microarray data,and study the relationship between coding sequence divergence and expression divergence. First,we find a strong positive correlation between...
متن کاملRapid divergence in expression between duplicate genes inferred from microarray data.
For more than 30 years, expression divergence has been considered as a major reason for retaining duplicated genes in a genome, but how often and how fast duplicate genes diverge in expression has not been studied at the genomic level. Using yeast microarray data, we show that expression divergence between duplicate genes is significantly correlated with their synonymous divergence (K(S)) and a...
متن کاملAsymmetric sequence divergence of duplicate genes.
Much like humans, gene duplicates may be created equal, but they do not stay that way for long. For four completely sequenced genomes we show that 20%-30% of duplicate gene pairs show asymmetric evolution in the amino acid sequence of their protein products. That is, one of the duplicates evolves much faster than the other. The greater this asymmetry, the greater the ratio Ka/Ks of amino acid s...
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ژورنال
عنوان ژورنال: Trends in Genetics
سال: 2007
ISSN: 0168-9525
DOI: 10.1016/j.tig.2007.02.005